Yes, fatigue is listed as a common adverse reaction in the FDA prescribing information for Wegovy (semaglutide 2.4 mg for weight management)
Although most studies included several medications, current guidelines recommend selecting GLP1-RAs and SGLT2is on the basis of their clinically proven benefits rather than class alone
Patients who stop or do not follow structured exercise or meal planning may see weight return faster, as well
Fang Y, Ji L, Zhu C, Xiao Y, Zhang J, Lu J, et al
It is also contraindicated in patients with a history of pancreatitis or gastrointestinal issues since it increases gastrointestinal emptying time which can intensify symptoms
Because it is an injectable medication, it requires a prescription from a healthcare provider